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Last updated
July 26, 2025

Alzheimers

Air pollution and Alzheimer's disease research has uncovered groundbreaking mechanisms showing exactly how environmental toxins contribute to memory loss and neurodegeneration. Scientists at Scripps Research discovered that a chemical process called S-nitrosylation, triggered by pollutants in air pollution, smoke, and pesticides, disrupts brain cell function by preventing new neural connections. Remarkably, when researchers blocked this process in Alzheimer's mouse models, they partially reversed memory loss, opening new pathways for potential drug treatments. Explore the compelling evidence linking air pollution to cognitive decline and the promising therapeutic approaches emerging from this research.
  • A chemical change called S-nitrosylation disrupts brain cell function by preventing cells from making new connections. This process can be triggered by inflammation, ageing, or toxins found in air pollution, smoke, and pesticides. (Cross, 2025)
  • Scientists at Scripps Research found that blocking S-nitrosylation in a key brain protein partially reversed memory loss in Alzheimer’s mouse models and nerve cells from human stem cells. (Cross, 2025)
  • The study revealed how pollutants can contribute to memory loss and neurodegenerative diseases, potentially leading to new drug treatments for Alzheimer’s disease. (Cross, 2025)

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